Under the guidance of All India Council for Technical Education (AICTE), Maharaja Sayajirao University of Baroda conducts Graduate Pharmacy Aptitude Test, which is also known as GPAT entrance exam. The all-India level entrance test is conducted to admit students in postgraduate program in pharmacy - Master of Pharmacy (M. Pharm). The final selection of the candidates is totally based on their performance in Graduate Pharmacy Aptitude Test (GPAT).
Syllabus
To prepare for GPAT entrance test, one has to study all the basics of pharmacy - natural products (Pharmacognosy & Phytochemistry), Pharmacology, Pharmaceutics, Pharmaceutical Jurisprudence, Pharmaceutical Analysis, Biochemistry, Microbiology and Clinical Pharmacy.
Natural Products
Standardization of raw materials and herbal products, WHO guidelines. Quantitative microscopy including modern techniques used for evaluation. Biotechnological principles and techniques for plant development, Tissue culture, Pharmacognosy & Phytochemistry - Chemistry, tests, isolation, characterization and estimation of phytopharmaceuticals belonging to the group of Alkaloids, Glycosides, Terpenoids, Ster oids, Bioflavanoids, Purines, Guggul lipids, Pharmacognosy of crude drugs that contain the above constituents.
Pharmacology
Pharmacology of Autocoids, Hormones, Hormone antagonists, chemotherapeutic agents including anticancer drugs, Bioassays, Immuno Pharmacology. Drugs acting on the blood & blood forming organs. Drugs acting on the renal system, General pharmacological principles including Toxicology. Drug interaction. Pharmacology of drugs acting on Central nervous system, Cardiovascular system, Autonomic nervous system, Gastro intestinal system and Respiratory system.
Medicinal Chemistry
Structure, nomenclature, classification, synthesis, SAR and metabolism of the following category of drugs, which are official in Indian Pharmacopoeia and British Pharmacopoeia, Introduction to drug design. Stereochemistry of drug molecules, Antiprotozoal drugs, Antiviral, Antitubercular, Antimalarial, Anticancer, Antiamoebic drugs. Diagnostic agents, Hypnotics and Sedatives, Analgesics, NSAIDS, Neuroleptics, Antidepressants, Anxiolytics, Anticonvulsants, Antihistaminics, Local Anaesthetics, Cardio Vascular drugs - Antianginal agents Vasodilators, Adrenergic & Cholinergic drugs, Cardiotonic agents, Diuretics, Anti-hypertensive drugs, Hypoglycemic agents, Antilipedmic agents, Coagulants, Anticoagulants, Antiplatelet agents. Chemotherapeutic agents - Antibiotics, Antibacterials, Sulphadrugs.
Pharmaceutics
Formulation and preparation of cosmetics - lipstick, shampoo, creams, nail preparations and dentifrices, Pharmaceutical calculations, Development, manufacturing standards Q.C. limits, labeling, as per the pharmacopoeial requirements. Storage of different dosage forms and new drug delivery systems. Biopharmaceutics and Pharmacokinetics and their importance in formulation.
Pharmaceutical Jurisprudence
The topics include Drugs and cosmetics Act and rules with respect to manufacture, sales and storage, Pharmacy Act and Pharmaceutical ethics.
Biochemistry
General principles of immunology, Immunological, Metabolism of carbohydrate, lipids, proteins, Methods to determine, kidney & liver function have to be studied by the students while preparing for the exam. Lipid profiles, Biochemical role of hormones, Vitamins, Enzymes, Nucleic acids, Bioenergetics.
Microbiology
Applications of microorganisms in Bio Conversions and in Pharmaceutical industry, Methods of preparation of official sera and vaccines are the topics generally asked in GPAT exam. In addition to this, one also has to be thorough with the concepts of Serological and diagnostics tests and Principles and methods of microbiological assays of the Pharmacopoeia.
